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Lab notes
Accelerating the search for antimicrobial peptides with Google Antigravity
Accelerating the search for novel antimicrobial peptides using Google Antigravity for Science.
Pengfei Tian, Maxwell L. Bileschi, Zoi Tsangalidou, Sukhdeep Singh and Lucy J. Colwell
New antibiotics are urgently needed to help with rising levels of antimicrobial resistance, but searching for new therapeutics is often a slow, labor-intensive process. With Google Antigravity, our agentic development platform, this process can now be made easier.
Google Antigravity provides an agentic science workbench that empowers biologists to discover, structurally evaluate, and prioritize promising targets quickly, compressing what used to be a fragmented search over multiple databases into a single session. It also helps researchers scan through millions of previously uncharacterized proteins in the UniProt database using ProtNLM, a model that predicts biological function from amino acid sequences.
This technical walkthrough shows how biologists used Google Antigravity to uncover a novel antimicrobial peptide candidate which has predicted activity against the pathogens involved in respiratory tract infections. The lead identified here is now undergoing wet-lab validation.
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